Revealing vascular abnormalities and measuring small vessel density in multiple sclerosis lesions using USPIO

Background and Purpose: Multiple Sclerosis (MS) is a progressive, inflammatory, neuro-degenerative disease of the central nervous system (CNS) characterized by a wide range of histopathological features including vascular abnormalities. In this study, an ultra-small superparamagnetic iron oxide (USP...

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Bibliographic Details
Main Authors: Sagar Buch, Karthikeyan Subramanian, Pavan K. Jella, Yongsheng Chen, Zhen Wu, Kamran Shah, Evanthia Bernitsas, Yulin Ge, E. Mark Haacke
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220303624