Enhanced regional AT2-receptor and PKCε expression during cardioprotection induced by AT1-receptor blockade after reperfused myocardial infarction
We assessed the effects of the angiotensin II (Ang II) type 1 receptor (AT 1 -receptor) blocker, candesartan, (CN, 1 mg/kg i.v. over 30 minutes pre-ischaemia) alone or after intracoronary administration of Ang II type 2 receptor (AT 2 -receptor) blocker (PD 123319), protein kinase C (PKC) inhibitor...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2001-06-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.3317/jraas.2001.015 |