Enhanced regional AT2-receptor and PKCε expression during cardioprotection induced by AT1-receptor blockade after reperfused myocardial infarction

We assessed the effects of the angiotensin II (Ang II) type 1 receptor (AT 1 -receptor) blocker, candesartan, (CN, 1 mg/kg i.v. over 30 minutes pre-ischaemia) alone or after intracoronary administration of Ang II type 2 receptor (AT 2 -receptor) blocker (PD 123319), protein kinase C (PKC) inhibitor...

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Bibliographic Details
Main Authors: Bodh I Jugdutt, Mohammed Balghith
Format: Article
Language:English
Published: SAGE Publications 2001-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2001.015