Immature and mature bone marrow-derived dendritic cells exhibit distinct intracellular mechanical properties

Abstract Dendritic cells (DCs) patrol the organism at an immature stage to detect the presence of pathogens. Once activated, these mature DCs reach the lymph nodes to activate antigen-specific T lymphocytes and thus initiate an adaptative immune response to control the pathogen. The migration of bot...

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Bibliographic Details
Main Authors: Antoine Leblanc-Hotte, Cindy Audiger, Geneviève Chabot-Roy, Félix Lombard-Vadnais, Jean-Sébastien Delisle, Yves-Alain Peter, Sylvie Lesage
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28625-w