LooplessFluxSampler: an efficient toolbox for sampling the loopless flux solution space of metabolic models

Abstract Background Uniform random sampling of mass-balanced flux solutions offers an unbiased appraisal of the capabilities of metabolic networks. Unfortunately, it is impossible to avoid thermodynamically infeasible loops in flux samples when using convex samplers on large metabolic models. Curren...

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Bibliographic Details
Main Authors: Pedro A. Saa, Sebastian Zapararte, Christopher C. Drovandi, Lars K. Nielsen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-023-05616-2