LooplessFluxSampler: an efficient toolbox for sampling the loopless flux solution space of metabolic models
Abstract Background Uniform random sampling of mass-balanced flux solutions offers an unbiased appraisal of the capabilities of metabolic networks. Unfortunately, it is impossible to avoid thermodynamically infeasible loops in flux samples when using convex samplers on large metabolic models. Curren...
Main Authors: | Pedro A. Saa, Sebastian Zapararte, Christopher C. Drovandi, Lars K. Nielsen |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-023-05616-2 |
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