Assessment of a Small Molecule Synthetic Lignan in Enhancing Oxidative Balance and Decreasing Lipid Accumulation in Human Retinal Pigment Epithelia

Assessment of a Small Molecule Synthetic Lignan in Enhancing Oxidative Balance and Decreasing Lipid Accumulation in Human Retinal Pigment Epithelia

Visual function depends on the intimate structural, functional and metabolic interactions between the retinal pigment epithelium (RPE) and the neural retina. The daily phagocytosis of the photoreceptor outer segment tips by the overlaying RPE provides essential nutrients for the RPE itself and photo...

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Bibliographic Details
Main Authors: Anuradha Dhingra, Rachel C. Sharp, Taewan Kim, Anatoliy V. Popov, Gui-Shuang Ying, Ralph A. Pietrofesa, Kyewon Park, Melpo Christofidou-Solomidou, Kathleen Boesze-Battaglia
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
antioxidant
inflammation
retina
ketogenesis
LGM2605
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/22/11/5764

Internet

https://www.mdpi.com/1422-0067/22/11/5764

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