Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats

Lead can damage neuron synapses in the hippocampus and cause synaptic plasticity losses, and learning, memory, and intelligence impairments. Previous studies have focused on the functional and structural plasticity of hippocampal synapses; however, the specific molecular mechanisms behind such impai...

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Bibliographic Details
Main Authors: Bo Zhang, Hang Li, Yan Wang, Yang Li, Zhongsheng Zhou, Xuejia Hou, Xiaowen Zhang, Te Liu
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323000611