Hydroquinone 5-<i>O</i>-Cinnamoyl Ester of Renieramycin M Suppresses Lung Cancer Stem Cells by Targeting Akt and Destabilizes c-Myc

Hydroquinone 5-<i>O</i>-Cinnamoyl Ester of Renieramycin M Suppresses Lung Cancer Stem Cells by Targeting Akt and Destabilizes c-Myc

Cancer stem cells (CSCs) are distinct cancer populations with tumorigenic and self-renewal abilities. CSCs are drivers of cancer initiation, progression, therapeutic failure, and disease recurrence. Thereby, novel compounds targeting CSCs offer a promising way to control cancer. In this study, the h...

Full description

Bibliographic Details
Main Authors: Nattamon Hongwiangchan, Nicharat Sriratanasak, Duangdao Wichadakul, Nithikoon Aksorn, Supakarn Chamni, Pithi Chanvorachote
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceuticals
Subjects:
lung cancer
cancer stem cell
Akt
mTOR
c-Myc
renieramycin M
Online Access:https://www.mdpi.com/1424-8247/14/11/1112

Internet

https://www.mdpi.com/1424-8247/14/11/1112

Similar Items