Pleiotropic effects of deubiquitinating enzyme Ubp5 on growth and pathogenesis of Cryptococcus neoformans.

Ubiquitination is a reversible protein modification that influences various cellular processes in eukaryotic cells. Deubiquitinating enzymes remove ubiquitin, maintain ubiquitin homeostasis and regulate protein degradation via the ubiquitination pathway. Cryptococcus neoformans is an important basid...

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Bibliographic Details
Main Authors: Wei Fang, Michael S Price, Dena L Toffaletti, Jennifer Tenor, Marisol Betancourt-Quiroz, Jennifer L Price, Wei-hua Pan, Wan-qing Liao, John R Perfect
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3375289?pdf=render