Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts

Vitamin C Activates the Folate-Mediated One-Carbon Cycle in C2C12 Myoblasts

Vitamin C (L-ascorbic acid, AA) is an essential cellular antioxidant and cofactor for several α-ketoglutarate-dependent dioxygenases. As an antioxidant, AA interacts with vitamin E to control oxidative stress. While several reports suggest an interaction of AA with folate (vitamin B9) in an...

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Bibliographic Details
Main Authors: Armando Alcazar Magana, Ralph L. Reed, Rony Koluda, Cristobal L. Miranda, Claudia S. Maier, Jan F. Stevens
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Antioxidants
Subjects:
vitamin c
folic acid
one-carbon metabolism
c2c12 cells
metabolomics
mass spectrometry
ascorbic acid
Online Access:https://www.mdpi.com/2076-3921/9/3/217

Internet

https://www.mdpi.com/2076-3921/9/3/217

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