Imbalance between the Serum Levels of VEGF, MMP-2 and α1-AT in Patients with Diabetic Retinopathy

Imbalance between the Serum Levels of VEGF, MMP-2 and α1-AT in Patients with Diabetic Retinopathy

Background: Diabetic Retinopathy (DR), a microvascular complication of Type 2 Diabetes Mellitus (T2DM) is due to retinal neovascularization mediated by Vascular Endothelial Growth Factor (VEGF). Neovascularization involves proteolytic degradation of Extracellular Matrix (ECM) by Matrix Metalloprotea...

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Bibliographic Details
Main Authors: Kuksal Ashansha Mohan, Mamatha Kunder, Sharath Balakrishna
Format: Article
Language:English
Published: Krishna Vishwa Vidyapeeth (Deemed to be University), Karad 2021-10-01
Series:Journal of Krishna Institute of Medical Sciences University
Subjects:
diabetic retinopathy
vascular endothelial growth factor
matrix metalloproteases -2
alpha 1- antitrypsin
angiogenesis
extracellular matrix degradation
Online Access:https://www.jkimsu.com/jkimsu-vol10no4/JKIMSU,%20Vol.%2010,%20No.%204,%20October-December%202021%20Page%2013-20.pdf

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https://www.jkimsu.com/jkimsu-vol10no4/JKIMSU,%20Vol.%2010,%20No.%204,%20October-December%202021%20Page%2013-20.pdf

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