RAS Dimers: The Novice Couple at the RAS-ERK Pathway Ball

Signals conveyed through the RAS-ERK pathway constitute a pivotal regulatory element in cancer-related cellular processes. Recently, RAS dimerization has been proposed as a key step in the relay of RAS signals, critically contributing to RAF activation. RAS clustering at plasma membrane microdomains...

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Bibliographic Details
Main Authors: Ana Herrero, Piero Crespo
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/10/1556