RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation.

RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation.

RhoA plays a multifaceted role in platelet biology. During platelet development, RhoA has been proposed to regulate endomitosis, proplatelet formation, and platelet release, in addition to having a role in platelet activation. These processes were previously studied using pharmacological inhibitors...

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Bibliographic Details
Main Authors: Aae Suzuki, Jae-Won Shin, Yuhuan Wang, Sang H Min, Morty Poncz, John K Choi, Dennis E Discher, Chris L Carpenter, Lurong Lian, Liang Zhao, Yangfeng Wang, Charles S Abrams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720647?pdf=render

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http://europepmc.org/articles/PMC3720647?pdf=render

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