Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2

Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2

Neutrophils are critical in the immune response to infective agents and have multiple effector strategies including the production of extracellular traps termed NETs. Here the authors show a link between NET production and Th17 differentiation which mechanistically occurs downstream of TLR2 signalli...

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Bibliographic Details
Main Authors: Alicia S. Wilson, Katrina L. Randall, Jessica A. Pettitt, Julia I. Ellyard, Antje Blumenthal, Anselm Enders, Benjamin J. Quah, Tobias Bopp, Christopher R. Parish, Anne Brüstle
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28172-4

Internet

https://doi.org/10.1038/s41467-022-28172-4

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