RegB Kinase Activity Is Controlled in Part by Monitoring the Ratio of Oxidized to Reduced Ubiquinones in the Ubiquinone Pool

ABSTRACT RegB is a membrane-spanning sensor kinase responsible for redox regulation of a wide variety of metabolic processes in numerous proteobacterial species. Here we show that full-length RegB purified from Escherichia coli membranes contains bound ubiquinone. Four conserved residues in the memb...

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Bibliographic Details
Main Authors: Jiang Wu, Carl E. Bauer
Format: Article
Language:English
Published: American Society for Microbiology 2010-12-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00272-10