The Mucus Binding Factor Is Not Necessary for <i>Lacticaseibacillus rhamnosus</i> CRL1505 to Exert Its Immunomodulatory Activities in Local and Distal Mucosal Sites

The Mucus Binding Factor Is Not Necessary for <i>Lacticaseibacillus rhamnosus</i> CRL1505 to Exert Its Immunomodulatory Activities in Local and Distal Mucosal Sites

Both viable and non-viable orally administered <i>Lacticaseibacillus rhamnosus</i> CRL1505 modulate immunity in local (intestine) and distal (respiratory) mucosal sites. So, intestinal adhesion and colonization are not necessary for this probiotic strain to exert its immunomodulatory eff...

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Bibliographic Details
Main Authors: Kae Tomotsune, Fernanda Raya Tonetti, Hiroya Mizuno, Mariano Elean, Kohtaro Fukuyama, Binghui Zhou, Wakako Ikeda-Ohtsubo, Keita Nishiyama, Akihiro Yamamura, Hideaki Karasawa, Shinobu Ohnuma, Akira Horii, Tadao Saito, Haruki Kitazawa, Julio Villena
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
immunobiotic
mucus-binding factor mutant
<i>Lacticaseibacillus rhamnsous</i> CRL1505
intestinal immunity
respiratory immunity
probiotic
Online Access:https://www.mdpi.com/1422-0067/23/22/14357

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https://www.mdpi.com/1422-0067/23/22/14357

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