MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus

MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is a common and devastating autoimmune disease, characterized by a dysregulated adaptive immune response against intracellular antigens, which involves both autoreactive T and B cells. In SLE, mainly intracellular autoantigens generate autoantibodies and these asse...

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Bibliographic Details
Main Authors: Estefania Ugarte-Berzal, Lise Boon, Erik Martens, Vasily Rybakin, Daniel Blockmans, Jennifer Vandooren, Paul Proost, Ghislain Opdenakker
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
matrix metalloproteinase-9
immune complexes
immunoglobulins
systemic lupus erythematosus
drug-induced lupus erythematosus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00538/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00538/full

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