RNA and phosphoprotein profiles of TP53- and PTEN-knockouts in MCF10A at baseline and responding to DNA damage

RNA and phosphoprotein profiles of TP53- and PTEN-knockouts in MCF10A at baseline and responding to DNA damage

Abstract A wealth of proteogenomic data has been generated using cancer samples to deepen our understanding of the mechanisms of cancer and how biological networks are altered in association with somatic mutation of tumor suppressor genes, such as TP53 and PTEN. To generate functional signatures of...

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Autors principals: ChenWei Lin, Regine M. Schoenherr, Uliana J. Voytovich, Richard G. Ivey, Jacob J. Kennedy, Jeffrey R. Whiteaker, Pei Wang, Amanda G. Paulovich
Format: Article
Idioma:English
Publicat: Nature Portfolio 2024-01-01
Col·lecció:Scientific Data
Accés en línia:https://doi.org/10.1038/s41597-023-02829-1

Internet

https://doi.org/10.1038/s41597-023-02829-1

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