Canagliflozin, an Inhibitor of the Na<sup>+</sup>-Coupled D-Glucose Cotransporter, SGLT2, Inhibits Astrocyte Swelling and Brain Swelling in Cerebral Ischemia

Canagliflozin, an Inhibitor of the Na<sup>+</sup>-Coupled D-Glucose Cotransporter, SGLT2, Inhibits Astrocyte Swelling and Brain Swelling in Cerebral Ischemia

Brain swelling is a major cause of death and disability in ischemic stroke. Drugs of the gliflozin class, which target the Na<sup>+</sup>-coupled D-glucose cotransporter, SGLT2, are approved for type 2 diabetes mellitus (T2DM) and may be beneficial in other conditions, but data in cerebr...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Bosung Shim, Jesse A. Stokum, Mitchell Moyer, Natalya Tsymbalyuk, Orest Tsymbalyuk, Kaspar Keledjian, Svetlana Ivanova, Cigdem Tosun, Volodymyr Gerzanich, J. Marc Simard
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: MDPI AG 2023-09-01
Цуврал:Cells
Нөхцлүүд:
cerebral ischemia
stroke
brain swelling
diabetes
astrocyte
SGLT2
Онлайн хандалт:https://www.mdpi.com/2073-4409/12/18/2221

Интернэт

https://www.mdpi.com/2073-4409/12/18/2221

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