Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice

Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice

Abstract One goal of regenerative medicine is to rejuvenate tissues and extend lifespan by restoring the function of endogenous aged stem cells. However, evidence that somatic stem cells can be targeted in vivo to extend lifespan is still lacking. Here, we demonstrate that after a short systemic tre...

Full description

Bibliographic Details
Main Authors: Sara Montserrat-Vazquez, Noelle J. Ali, Francesca Matteini, Javier Lozano, Tu Zhaowei, Eva Mejia-Ramirez, Gina Marka, Angelika Vollmer, Karin Soller, Mehmet Sacma, Vadim Sakk, Loris Mularoni, Jan Philipp Mallm, Mireya Plass, Yi Zheng, Hartmut Geiger, M. Carolina Florian
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-022-00275-y

Internet

https://doi.org/10.1038/s41536-022-00275-y

Similar Items