Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2

Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2

Abstract Nasopharyngeal carcinoma (NPC) is a malignant tumor of epithelial origin in head and neck with high incidence rate in South China, Southeast Asia and North Africa. The intervention of tumor-associated macrophages (Mφs) (TAMs)-mediated immunosuppression is a potential therapeutic strategy ag...

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Bibliographic Details
Main Authors: Xiaowei Zhang, Shen’er Qian, Ping’an Wu, Benquan Yu, Danhui Yin, Xia Peng, Shisheng Li, Zian Xiao, Zuozhong Xie
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Cell Communication and Signaling
Subjects:
Tumor-associated macrophages
Itaconic acid
Nasopharyngeal carcinoma
Immune escape
TET2
Online Access:https://doi.org/10.1186/s12964-024-01799-0

Internet

https://doi.org/10.1186/s12964-024-01799-0

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