Detection of novel Plasmodium falciparum coronin gene mutations in a recrudescent ACT-treated patient in South-Western Nigeria

Detection of novel Plasmodium falciparum coronin gene mutations in a recrudescent ACT-treated patient in South-Western Nigeria

BackgroundRoutine surveillance for antimalarial drug resistance is critical to sustaining the efficacy of artemisinin-based Combination Therapies (ACTs). Plasmodium falciparum kelch-13 (Pfkelch-13) and non-Pfkelch-13 artemisinin (ART) resistance-associated mutations are uncommon in Africa. We invest...

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Bibliographic Details
Main Authors: Olusola Ajibaye, Yetunde Adeola Olukosi, Eniyou C. Oriero, Mary Aigbiremo Oboh, Bamidele Iwalokun, Ikechukwu Chidiebere Nwankwo, Chinaza Favour Nnam, Olawunmi Victoria Adaramoye, Somadina Chukwemeka, Judith Okanazu, Eniafe Gabriel, Emmanuel Oluwadare Balogun, Alfred Amambua-Ngwa
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
malaria
Plasmodium falciparum
coronin
polymorphisms
artemisinin resistance
lumefantrine
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1366563/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2024.1366563/full

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