PACAP/GCGa Is an Important Modulator of the Amphioxus CNS-Hatschek’s Pit Axis, the Homolog of the Vertebrate Hypothalamic-Pituitary Axis in the Basal Chordates

PACAP/GCGa Is an Important Modulator of the Amphioxus CNS-Hatschek’s Pit Axis, the Homolog of the Vertebrate Hypothalamic-Pituitary Axis in the Basal Chordates

The Hatschek’s pit in the cephalochordate amphioxus, an invertebrate deuterostome basal to chordates is suggested to be the functional homolog structure of the vertebrate adenohypophysis based on anatomy and expression of homologous neuroendocrine genes. However, the endocrine potential of the cepha...

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Bibliographic Details
Main Authors: Jason S. W. On, Liuru Su, Hong Shen, Aloysius W. R. Arokiaraj, João C. R. Cardoso, Guang Li, Billy K. C. Chow
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Endocrinology
Subjects:
CNS-Hatschek’s pit axis
hypothalamic-pituitary axis
amphioxus
PACAP/GCG
GHl
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.850040/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.850040/full

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