An exploratory pilot analysis of the optimal pellet number in 100 mg of itraconazole capsule to maximize the surface area to satisfy the Noyes–Whitney equation

An exploratory pilot analysis of the optimal pellet number in 100 mg of itraconazole capsule to maximize the surface area to satisfy the Noyes–Whitney equation

Introduction Recalcitrant dermatophytoses is on the rise. With increasing microbiological resistance and clinical failures reported to terbinafine, itraconazole (ITR) is being increasingly used for the condition. ITR has an unpredictable bioavailability and quality variation among brands is known to...

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Bibliographic Details
Main Authors: Kabir Sardana, Ananta Khurana, Sanjeet Panesar, Ajeet Singh
Format: Article
Language:English
Published: Taylor & Francis Group 2021-10-01
Series:Journal of Dermatological Treatment
Subjects:
itraconazole
pellet
noyes–whitney
surface area
absorption
dissolution
Online Access:http://dx.doi.org/10.1080/09546634.2019.1708848

Internet

http://dx.doi.org/10.1080/09546634.2019.1708848

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