Potential predictive value of circulating tumor DNA (ctDNA) mutations for the efficacy of immune checkpoint inhibitors in advanced triple-negative breast cancer

Potential predictive value of circulating tumor DNA (ctDNA) mutations for the efficacy of immune checkpoint inhibitors in advanced triple-negative breast cancer

Background: In recent years, tumor immunotherapy has become a viable treatment option for triple negative breast cancer (TNBC). Among these, immune checkpoint inhibitors (ICIs) have demonstrated good efficacy in advanced TNBC patients with programmed death-ligand 1 (PD-L1) positive expression. Howev...

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Bibliographic Details
Main Authors: Qiaorui Tan, Yajing Chi, Mu Su, Jinxing Zhou, Dongdong Zhou, Fangchao Zheng, Xiaochu Man, Shujuan Sun, Jie Huang, Huihui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Genetics
Subjects:
triple-negative breast cancer
immune checkpoint inhibitors
ctDNA
next-generation sequencing
efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1125970/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1125970/full

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