Potential predictive value of circulating tumor DNA (ctDNA) mutations for the efficacy of immune checkpoint inhibitors in advanced triple-negative breast cancer

Potential predictive value of circulating tumor DNA (ctDNA) mutations for the efficacy of immune checkpoint inhibitors in advanced triple-negative breast cancer

Background: In recent years, tumor immunotherapy has become a viable treatment option for triple negative breast cancer (TNBC). Among these, immune checkpoint inhibitors (ICIs) have demonstrated good efficacy in advanced TNBC patients with programmed death-ligand 1 (PD-L1) positive expression. Howev...

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Bibliographic Details
Main Authors:	Qiaorui Tan, Yajing Chi, Mu Su, Jinxing Zhou, Dongdong Zhou, Fangchao Zheng, Xiaochu Man, Shujuan Sun, Jie Huang, Huihui Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Genetics
Subjects:	triple-negative breast cancer immune checkpoint inhibitors ctDNA next-generation sequencing efficacy
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1125970/full

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