Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics

Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics

A series of new chiral benzisoselenazol-3(2<i>H</i>)-ones and their corresponding diselenides bearing an <i>o</i>-amido function substituted on the nitrogen atom with various aliphatic and aromatic moieties were synthesized. All derivatives representing pairs of enantiomers o...

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Bibliographic Details
Main Authors: Anna Laskowska, Agata Joanna Pacuła-Miszewska, Angelika Długosz-Pokorska, Anna Janecka, Andrzej Wojtczak, Jacek Ścianowski
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Materials
Subjects:
benzisoselenazol-3(2<i>H</i>)-ones
diselenides
pharmacophore
antioxidant activity
antiproliferative activity
Online Access:https://www.mdpi.com/1996-1944/15/6/2068

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https://www.mdpi.com/1996-1944/15/6/2068

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