Bioinformatics and multiepitope DNA immunization to design rational snake antivenom.
Snake venom is a potentially lethal and complex mixture of hundreds of functionally diverse proteins that are difficult to purify and hence difficult to characterize. These difficulties have inhibited the development of toxin-targeted therapy, and conventional antivenom is still generated from the s...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-06-01
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| Series: | PLoS Medicine |
| Online Access: | http://europepmc.org/articles/PMC1472699?pdf=render |