Network Analysis Reveals A Signaling Regulatory Loop in the PIK3CA-mutated Breast Cancer Predicting Survival Outcome

Mutated genes are rarely common even in the same pathological type between cancer patients and as such, it has been very challenging to interpret genome sequencing data and difficult to predict clinical outcomes. PIK3CA is one of a few genes whose mutations are relatively popular in tumors. For exam...

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Bibliographic Details
Main Authors: Shauna R. McGee, Chabane Tibiche, Mark Trifiro, Edwin Wang
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022917300451