Dynamics of N6‐methyladenosine modification during aging and their potential roles in the degeneration of intervertebral disc

Dynamics of N6‐methyladenosine modification during aging and their potential roles in the degeneration of intervertebral disc

Abstract Background The N6‐methyladenosine (m6A) dynamics in the progression of intervertebral disc (IVD) aging remain largely unknown. This study aimed to explore the distribution and pattern of m6A modification in nucleus pulpous (NP) tissues of rats at different ages. Methods Histological stainin...

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Bibliographic Details
Main Authors: Libangxi Liu, Hong Sun, Yang Zhang, Chang Liu, Yong Zhuang, Miao Liu, Xuezheng Ai, Dan Long, Bo Huang, Changqing Li, Yue Zhou, Shiwu Dong, Chencheng Feng
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:JOR Spine
Subjects:
aging
epigenetic regulation
intervertebral disc degeneration
m6A modification
nucleus pulposus
Online Access:https://doi.org/10.1002/jsp2.1316

Internet

https://doi.org/10.1002/jsp2.1316

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