Molecular imaging of HER2 expression in breast cancer patients using a novel peptide-based tracer 99mTc-HP-Ark2: a pilot study

Molecular imaging of HER2 expression in breast cancer patients using a novel peptide-based tracer 99mTc-HP-Ark2: a pilot study

Abstract Background Due to the temporal and spatial heterogeneity of human epidermal growth factor receptor 2 (HER2) expression in breast tumors, immunohistochemistry (IHC) cannot accurately reflect the HER2 status in real time, which may cause misguided treatment decisions. HER2-specific imaging ca...

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Bibliographic Details
Main Authors: Jiyun Shi, Shuaifan Du, Rongxi Wang, Hannan Gao, Qi Luo, Guozhu Hou, Yidong Zhou, Zhaohui Zhu, Fan Wang
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Translational Medicine
Subjects:
SPECT/CT
HER2
Breast cancer
99mTc
Trastuzumab
Online Access:https://doi.org/10.1186/s12967-022-03865-y

Internet

https://doi.org/10.1186/s12967-022-03865-y

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