Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling

Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling

Background: The present study aimed to investigate the protective effect of the water extract of Amydrium sinense (Engl.) H. Li (ASWE) against hepatic fibrosis (HF) and clarify the underlying mechanism.Methods: The chemical components of ASWE were analysed by a Q-Orbitrap high-resolution mass spectr...

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Bibliographic Details
Main Authors: Jingyan Li, Bingmin Wu, Lishan Zeng, Ying Lin, Qiuhe Chen, Haixia Wang, Lin An, Jiajun Zhang, Siyan Chen, Junying Huang, Ruoting Zhan, Guifang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Pharmacology
Subjects:
Amydrium sinense
hepatic fibrosis
carbon tetrachloride
α-SMA
Stat3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1101703/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1101703/full

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