p16INK4a Expression and Absence of Activated B-RAF Are Independent Predictors of Chemosensitivity in Melanoma Tumors

Metastatic cutaneous melanoma is highly resistant to cytotoxic drugs, and this contributes to poor prognosis. In vivo studies on the chemosensitivity of metastatic melanoma are rare and hampered by poor response rates to systemic chemotherapeutics. Patients who undergo isolated limb infusion (ILI) w...

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Main Authors: Stuart J. Gallagher, John F. Thompson, James Indsto, Lyndee L. Scurr, Margaret Lett, Bo-Fu Gao, Ruth Dunleavey, Graham J. Mann, Richard F. Kefford, Helen Rizos
פורמט: Article
שפה:English
יצא לאור: Elsevier 2008-11-01
סדרה:Neoplasia: An International Journal for Oncology Research
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S1476558608800206