$Stereoselective domino assembling of five molecules: one-pot approach to $(2^\primeR^*,3S^*,4^\primeR^*)$-$2^\prime,4^\prime$-diaryl-$1^\prime,4^\prime$-dihydro-$2^\primeH $-spiro[indoline-$3,3^\prime$-pyridines]$

Stereoselective domino assembling of five molecules: one-pot approach to $(2^\primeR^,3S^,4^\primeR^*)$-$2^\prime,4^\prime$-diaryl-$1^\prime,4^\prime$-dihydro-$2^\primeH $-spiro[indoline-$3,3^\prime$-pyridines]

A new stereoselective multicomponent reaction has been found: domino assembling of two equivalents of benzaldehyde, malononitrile, oxindole and excess of ammonium acetate in acetonitrile resulted in the formation of previously unknown $(2^\primeR^*,3S^*,4^\primeR^*)$-$6^\prime$-amino-2-oxo-$2^\prime...

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Bibliographic Details
Main Authors:	Ryzhkov, Fedor V., Elinson, Michail N., Ryzhkova, Yuliya E., Vereshchagin, Anatoly N., Goloveshkin, Alexander S., Egorov, Mikhail P.
Format:	Article
Language:	English
Published:	Académie des sciences 2020-06-01
Series:	Comptes Rendus. Chimie
Subjects:	Malononitrile Oxindole Domino reaction Spiro[indoline-3 3$^\prime$-pyridine] Knoevenagel condensation Michael addition
Online Access:	https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.13/

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https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.13/

Stereoselective domino assembling of five molecules: one-pot approach to $(2^\primeR^*,3S^*,4^\primeR^*)$-$2^\prime,4^\prime$-diaryl-$1^\prime,4^\prime$-dihydro-$2^\primeH $-spiro[indoline-$3,3^\prime$-pyridines]

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Stereoselective domino assembling of five molecules: one-pot approach to $(2^\primeR^,3S^,4^\primeR^*)$-$2^\prime,4^\prime$-diaryl-$1^\prime,4^\prime$-dihydro-$2^\primeH $-spiro[indoline-$3,3^\prime$-pyridines]