Discovering the Protective Effects of Quercetin on Aflatoxin B1-Induced Toxicity in Bovine Foetal Hepatocyte-Derived Cells (BFH12)

Discovering the Protective Effects of Quercetin on Aflatoxin B1-Induced Toxicity in Bovine Foetal Hepatocyte-Derived Cells (BFH12)

Aflatoxin B1 (AFB1) induces lipid peroxidation and mortality in bovine foetal hepatocyte-derived cells (BFH12), with underlying transcriptional perturbations associated mainly with cancer, cellular damage, inflammation, bioactivation, and detoxification pathways. In this cell line, curcumin and resv...

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Bibliographic Details
Main Authors: Marianna Pauletto, Mery Giantin, Roberta Tolosi, Irene Bassan, Anisa Bardhi, Andrea Barbarossa, Ludovica Montanucci, Anna Zaghini, Mauro Dacasto
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Toxins
Subjects:
aflatoxin B1
quercetin
lipid peroxidation
CYP3A
NQO1
bovine
Online Access:https://www.mdpi.com/2072-6651/15/9/555

Internet

https://www.mdpi.com/2072-6651/15/9/555

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