Immune checkpoints in chronic obstructive pulmonary disease

Cell-mediated immune responses are vital to the body's defence against infection and play a key role in tumour immunity. T-cell activation and cytotoxic function is tightly regulated by a series of immune-regulatory receptor–ligand interactions or immune checkpoints. These controls limit immune...

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Bibliographic Details
Main Author: Tom M.A. Wilkinson
Format: Article
Language:English
Published: European Respiratory Society 2017-06-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/26/144/170045.full