A computational approach to analyze the missense mutations in human angiogenin variants leading to amyotrophic lateral sclerosis
The most detrimental missense mutations of angiogenin causing Amyotrophic lateral sclerosis were identified computationally and the substrate binding efficiencies of these mutations were also analyzed. Out of 12 variants, I-Mutant 2.0, SIFT and PolyPhen programs identified 3 variants that were less...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Bangladesh Pharmacological Society
2013-11-01
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| Series: | Bangladesh Journal of Pharmacology |
| Subjects: | |
| Online Access: | https://www.banglajol.info/index.php/BJP/article/view/15259 |