The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review
Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a novel coronavirus discovered in 2019 that caused the coronavirus disease 2019 (COVID19). During the last year, over 70 million people were infected and more than 1.5 million people died. Despite the tremendous number of people infected, childr...
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MDPI AG
2021-04-01
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Online Access: | https://www.mdpi.com/2075-4426/11/4/318 |
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author | Marcela Daniela Ionescu Roxana Taras Bianca Dombici Mihaela Balgradean Elena Camelia Berghea Alin Nicolescu |
author_facet | Marcela Daniela Ionescu Roxana Taras Bianca Dombici Mihaela Balgradean Elena Camelia Berghea Alin Nicolescu |
author_sort | Marcela Daniela Ionescu |
collection | DOAJ |
description | Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a novel coronavirus discovered in 2019 that caused the coronavirus disease 2019 (COVID19). During the last year, over 70 million people were infected and more than 1.5 million people died. Despite the tremendous number of people infected, children were less affected and presented milder forms of the disease. A short time after the pandemic was declared, a new hyperinflammatory syndrome resembling Kawasaki disease (KD) was described in children with confirmed or suspected SARS-CoV-2 infection named multisystem inflammatory syndrome in children (MIS-C). The incidence of MIS-C is low and it has a polymorphous clinical presentation, making the diagnosis difficult. Although the incidence is reduced, there is a high risk of cardiovascular complications. In order to raise awareness, we present the cases of two pediatric patients diagnosed with MIS-C in our clinic. |
first_indexed | 2024-03-10T12:11:46Z |
format | Article |
id | doaj.art-a4d57bf348f8472da05c914f05647432 |
institution | Directory Open Access Journal |
issn | 2075-4426 |
language | English |
last_indexed | 2024-03-10T12:11:46Z |
publishDate | 2021-04-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Personalized Medicine |
spelling | doaj.art-a4d57bf348f8472da05c914f056474322023-11-21T16:10:50ZengMDPI AGJournal of Personalized Medicine2075-44262021-04-0111431810.3390/jpm11040318The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature ReviewMarcela Daniela Ionescu0Roxana Taras1Bianca Dombici2Mihaela Balgradean3Elena Camelia Berghea4Alin Nicolescu5Department of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, RomaniaMarie Curie Emergency Children’s Hospital, 041451 Bucharest, RomaniaSevere acute respiratory coronavirus 2 (SARS-CoV-2) is a novel coronavirus discovered in 2019 that caused the coronavirus disease 2019 (COVID19). During the last year, over 70 million people were infected and more than 1.5 million people died. Despite the tremendous number of people infected, children were less affected and presented milder forms of the disease. A short time after the pandemic was declared, a new hyperinflammatory syndrome resembling Kawasaki disease (KD) was described in children with confirmed or suspected SARS-CoV-2 infection named multisystem inflammatory syndrome in children (MIS-C). The incidence of MIS-C is low and it has a polymorphous clinical presentation, making the diagnosis difficult. Although the incidence is reduced, there is a high risk of cardiovascular complications. In order to raise awareness, we present the cases of two pediatric patients diagnosed with MIS-C in our clinic.https://www.mdpi.com/2075-4426/11/4/318multisystem inflammatory syndrome in childrencytokinesKawasaki diseasepediatric COVID19—Kawasaki |
spellingShingle | Marcela Daniela Ionescu Roxana Taras Bianca Dombici Mihaela Balgradean Elena Camelia Berghea Alin Nicolescu The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review Journal of Personalized Medicine multisystem inflammatory syndrome in children cytokines Kawasaki disease pediatric COVID19—Kawasaki |
title | The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review |
title_full | The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review |
title_fullStr | The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review |
title_full_unstemmed | The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review |
title_short | The Challenging Diagnosis of Pediatric Multisystem Inflammatory Syndrome Associated with Sars-Cov-2 Infection-Two Case Reports and Literature Review |
title_sort | challenging diagnosis of pediatric multisystem inflammatory syndrome associated with sars cov 2 infection two case reports and literature review |
topic | multisystem inflammatory syndrome in children cytokines Kawasaki disease pediatric COVID19—Kawasaki |
url | https://www.mdpi.com/2075-4426/11/4/318 |
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