Uridylation regulates mRNA decay directionality in fission yeast

Uridylation regulates mRNA decay directionality in fission yeast

Abstract Cytoplasmic mRNA decay is effected by exonucleolytic degradation in either the 5’ to 3’ or 3’ to 5’ direction. Pervasive terminal uridylation is implicated in mRNA degradation, however, its functional relevance for bulk mRNA turnover remains poorly understood. In this study, we employ genom...

Full description

Bibliographic Details
Main Authors: Maciej Grochowski, Lidia Lipińska-Zubrycka, StJohn Townsend, Anna Golisz-Mocydlarz, Monika Zakrzewska-Płaczek, Grzegorz Brzyżek, Borna Jurković, Szymon Świeżewski, Markus Ralser, Michał Małecki
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-50824-w

Internet

https://doi.org/10.1038/s41467-024-50824-w

Similar Items