Accelerating fragment-based library generation by coupling high-performance photoreactors with benchtop analysis

Accelerating fragment-based library generation by coupling high-performance photoreactors with benchtop analysis

Herein we report a workflow coupling photoredox-nickel dual-catalyzed N-arylation reactions to benchtop analysis for the efficient generation of fragment-based libraries. Technological advances in photoreactor design facilitated reliable and reproducible experimentation. Knowledge on the reactivity...

Full description

Bibliographic Details
Main Authors: Quentin Lefebvre, Christophe Salomé, Thomas C. Fessard
Format: Article
Language:English
Published: Beilstein-Institut 2020-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
benchtop analytics
fragment-based library
heterocyclic sp2–sp3 fragments
n-arylation
photoredox-nickel dual catalysis
Online Access:https://doi.org/10.3762/bjoc.16.87

Internet

https://doi.org/10.3762/bjoc.16.87

Similar Items