Zoledronic acid blocks the interaction between breast cancer cells and regulatory T-cells

Zoledronic acid blocks the interaction between breast cancer cells and regulatory T-cells

Abstract Background Zoledronic acid (ZA), a nitrogen-containing bisphosphonate, inhibits osteoclastogenesis. Emerging evidence suggests that ZA has anti-tumor and anti-metastatic properties for breast cancer cells. In a mouse model of ZA-related osteonecrosis of the jaw, ZA administration was found...

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Bibliographic Details
Main Authors: Hsien Liu, Shih-Han Wang, Shin-Cheh Chen, Ching-Ying Chen, Tsun-Mei Lin
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Cancer
Subjects:
Regulatory T-cells
Zoledronic acid
Breast cancer
Immunomodulation
Online Access:http://link.springer.com/article/10.1186/s12885-019-5379-9

Internet

http://link.springer.com/article/10.1186/s12885-019-5379-9

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