Streptococcus agalactiae npx Is Required for Survival in Human Placental Macrophages and Full Virulence in a Model of Ascending Vaginal Infection during Pregnancy

Streptococcus agalactiae npx Is Required for Survival in Human Placental Macrophages and Full Virulence in a Model of Ascending Vaginal Infection during Pregnancy

ABSTRACT Streptococcus agalactiae, also known as group B Streptococcus (GBS), is a Gram-positive encapsulated bacterium that colonizes the gastrointestinal tract of 30 to 50% of humans. GBS causes invasive infection during pregnancy that can lead to chorioamnionitis, funisitis, preterm prelabor rupt...

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Bibliographic Details
Main Authors: Jacky Lu, Rebecca E. Moore, Sabrina K. Spicer, Ryan S. Doster, Miriam A. Guevara, Jamisha D. Francis, Kristen N. Noble, Lisa M. Rogers, Julie A. Talbert, Michelle L. Korir, Steven D. Townsend, David M. Aronoff, Shannon D. Manning, Jennifer A. Gaddy
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mBio
Subjects:
Streptococcus
infection
innate immunity
reactive oxygen species
ROS
Online Access:https://journals.asm.org/doi/10.1128/mbio.02870-22

Internet

https://journals.asm.org/doi/10.1128/mbio.02870-22

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