A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals.

The pathogenic yeast Cryptococcus neoformans causes cryptococcosis, a life-threatening fungal disease. C. neoformans has multiple virulence mechanisms that are non-host specific, induce damage and interfere with immune clearance. Microarray analysis of C. neoformans strains serially passaged in mice...

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Bibliographic Details
Main Authors: Erin E McClelland, Udupi A Ramagopal, Johanna Rivera, James Cox, Antonio Nakouzi, Moses M Prabu, Steven C Almo, Arturo Casadevall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005849&type=printable