Fascin-1 limits myosin activity in microglia to control mechanical characterization of the injured spinal cord

Fascin-1 limits myosin activity in microglia to control mechanical characterization of the injured spinal cord

Abstract Background Mechanical softening of the glial scar region regulates axonal regeneration to impede neurological recovery in central nervous system (CNS) injury. Microglia, a crucial cellular component of the glial scar, facilitate neuronal survival and neurological recovery after spinal cord...

Full description

Bibliographic Details
Main Authors: Jinxin Huang, Xuyang Hu, Zeqiang Chen, Fangru Ouyang, Jianjian Li, Yixue Hu, Yuanzhe Zhao, Jingwen Wang, Fei Yao, Juehua Jing, Li Cheng
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Neuroinflammation
Subjects:
Spinal cord injury
Microglia
Mechanical characterization
Fascin-1
Myosin
Online Access:https://doi.org/10.1186/s12974-024-03089-5

Internet

https://doi.org/10.1186/s12974-024-03089-5

Similar Items