Therapeutic monitoring of amiodarone: pharmacokinetics and evaluation of the relationship between effect and dose/concentration

Amiodarone is the most effective agent in the therapy of arrhythmias. However, the clinical effect of acute and chronic treatment is unclear and there are differences irrespective of comparable plasma/myocardial amiodarone and its metabolite desethylamiodarone concentations as well. Its unusual phar...

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Bibliographic Details
Main Authors: Erika Hrudikova Vyskocilova, Milan Grundmann, Jana Duricova, Ivana Kacirova
Format: Article
Language:English
Published: Palacký University Olomouc, Faculty of Medicine and Dentistry 2017-06-01
Series:Biomedical Papers
Subjects:
Online Access:https://biomed.papers.upol.cz/artkey/bio-201702-0003_Therapeutic_monitoring_of_amiodarone_pharmacokinetics_and_evaluation_of_the_relationship_between_effect_and_do.php