Prediction of hub genes and key pathways associated with the radiation response of human hematopoietic stem/progenitor cells using integrated bioinformatics methods

Abstract Hematopoietic stem cells (HSCs) are indispensable for the maintenance of the entire blood program through cytokine response. However, HSCs have high radiosensitivity, which is often a problem during radiation therapy and nuclear accidents. Although our previous study has reported that the c...

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Bibliographic Details
Main Authors: Yoshiaki Sato, Hironori Yoshino, Junya Ishikawa, Satoru Monzen, Masaru Yamaguchi, Ikuo Kashiwakura
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37981-6