Revisiting Circulating Extracellular Matrix Fragments as Disease Markers in Myelofibrosis and Related Neoplasms

Revisiting Circulating Extracellular Matrix Fragments as Disease Markers in Myelofibrosis and Related Neoplasms

Philadelphia chromosome-negative chronic myeloproliferative neoplasms (MPNs) arise due to acquired somatic driver mutations in stem cells and develop over 10–30 years from the earliest cancer stages (essential thrombocythemia, polycythemia vera) towards the advanced myelofibrosis stage with bone mar...

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Bibliographic Details
Main Authors: Hans Carl Hasselbalch, Peter Junker, Vibe Skov, Lasse Kjær, Trine A. Knudsen, Morten Kranker Larsen, Morten Orebo Holmström, Mads Hald Andersen, Christina Jensen, Morten A. Karsdal, Nicholas Willumsen
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
myeloproliferative neoplasms
MPNs
MPN
circulating extracellular matrix (ECM) proteins
serum procollagen III N-terminal propeptide (PIIINP)
procollagen type I C-terminal propeptide (PICP)
Online Access:https://www.mdpi.com/2072-6694/15/17/4323

Internet

https://www.mdpi.com/2072-6694/15/17/4323

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