The development of HIV vaccines targeting gp41 membrane-proximal external region (MPER): challenges and prospects

The development of HIV vaccines targeting gp41 membrane-proximal external region (MPER): challenges and prospects

Abstract A human immunodeficiency virus type-1 (HIV-1) vaccine which is able to effectively prevent infection would be the most powerful method of extinguishing pandemic of the acquired immunodeficiency syndrome (AIDS). Yet, achieving such vaccine remains great challenges. The membrane-proximal exte...

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Bibliographic Details
Main Authors: Huan Liu, Xiaojie Su, Lulu Si, Lu Lu, Shibo Jiang
Format: Article
Language:English
Published: Oxford University Press 2018-04-01
Series:Protein & Cell
Subjects:
HIV-1
gp41
MPER
vaccine
neutralizing antibodies
ADCC
Online Access:http://link.springer.com/article/10.1007/s13238-018-0534-7

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http://link.springer.com/article/10.1007/s13238-018-0534-7

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