Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells

Pure curcumin decreases the expression of WT1 by upregulation of miR-15a and miR-16-1 in leukemic cells

<p>Abstract</p> <p>Background</p> <p>Pure curcumin has been reported to down-regulate the expression of WT1 in leukemic cells. However, the molecular mechanism underlying the down-regulation of WT1 by curcumin is not completely delineated. The purpose of this present st...

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Bibliographic Details
Main Authors: Gao Shen-meng, Yang Jun-jun, Chen Chi-qi, Chen Jun-jie, Ye Li-ping, Wang Lu-yao, Wu Jian-bo, Xing Chong-yun, Yu Kang
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Curcumin
WT1
miR-15a
miR-16-1
Online Access:http://www.jeccr.com/content/31/1/27

Internet

http://www.jeccr.com/content/31/1/27

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