Implication of glutathione in the in vitro antiplasmodial mechanism of action of ellagic acid.

The search for new antimalarial chemotherapy has become increasingly urgent due to parasite resistance to current drugs. Ellagic acid (EA) is a polyphenol, recently found in various plant products, that has effective antimalarial activity in vitro and in vivo without toxicity. To further understand...

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Bibliographic Details
Main Authors: Patrice Njomnang Soh, Benoit Witkowski, Amandine Gales, Eric Huyghe, Antoine Berry, Bernard Pipy, Françoise Benoit-Vical
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3461036?pdf=render